Endocrine Abstracts

Introduction: Molecular testing play increasingly a significant role in pre-operative diagnosis of nodular goiter, as standard methods may not give conclusive decision in choosing optimal treatment approach. BRAF gene mutations are often discovered in the cytological specimens among the patients with papillary thyroid cancer. The aim of the study was to assess the incidence of BRAF T1799A mutation in cellular specimens derived from fine needle aspiration biopsy (FNAB)...

Introduction: Adrenocortical carcinoma (ACC) is a rare and aggressive tumor. Mitotane has been the mainstay adjuvant therapy of ACC. The study aimed to describe patients diagnosed with precocious puberty (PP) and other endocrinological disorders during mitotane treatment.Material and methods: This retrospective study enrolled four children with ACC treated with mitotane complicated by PP. The patients were diagnosed at C...